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MOTS-c has been studied in preclinical research models for its interactions with AMPK (AMP-activated protein kinase) signaling pathways, glucose metabolism regulation, and insulin sensitivity mechanisms, making it a research tool of particular interest to investigators studying mitochondrial biology, metabolic signaling, and cellular energetics

In addition, in vivo studies were conducted which showed that compound 77 could reduce serum uric acid levels at a dose of 10 mg.kg 1 [85]

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