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Reactive astrocytes and stem cells in spinal cord injury: good guys or bad guys

We found that PA triggered a ferroptosis-like injury program in the ENS, marked by increased iron import, reduced iron export, elevated labile iron and mitochondrial ROS, GPX4 suppression, lipid peroxidation, and neuronal dysfunction

5 Integrated therapeutic approaches The pathophysiology of DKD is multifactorial, involving hyperglycemia, intraglomerular hypertension, chronic inflammation, oxidative stress, and progressive fibrosis

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