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While these are encouraging reports, two recent large meta-analyses concluded that it still not possible to accurately predict the development of bipolar disorder, based on the early phenomenology (75, 76)

Furthermore, the fact that tracer retention in cortical regions increased with clinical disease severity, as estimated by the Revised ALS Functioning Rating Scale (ALSFRS-R), suggested that OS may be an important factor associated with the development of neurodegeneration in ALS patients [107]

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While this procedure offers a definitive cure, it permanently eliminates fertility, causing significant physical and psychological trauma to the patient [8]

Discussion We did not observe any statistically significant differences in GSH concentrations between HC and MA users in the ACC and DLPFC, or any relationships between brain GSH levels and drug use characteristics or behavioral outcomes of the participants