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beta-LAPachone ameliorates doxorubicin-induced cardiotoxicity via regulating autophagy and Nrf2 signalling pathways in mice

The IGF-1 signaling axis is widely studied for its involvement in cellular proliferation, metabolic regulation, tissue growth, and intracellular signaling mechanisms in preclinical research models

However, one challenging issue is to retain the biological activities (e.g., antioxidant, anti-microbial, and anti-inflammatory) and functional properties (e.g., emulsifying capacity, water holding capacity, and foaming stability) of PPDP during the extraction and the following processing stages, thus maintaining their health-promoting benefits

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The direct comparison upon using the same concentration of ruthenium of the molecular agent Ru(II)-OH and NP4 showed a significantly higher tumor accumulation of the nanoparticle formulation NP4 (Supplementary Fig