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2002;4:E131136

doi: 10.1038/s41598-021-97956-3 134 NewtonKStrasserAKayagakiNDixitVM

Therefore, the simplest nicotinamide nucleotide analogue system, 1-methylnicotinamide (MNA + , the oxidized form), and 1-methyldihydronicotinamide (MNAH, the reduced form) was used as comparison redox couple

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This process avoids adding external molecules since interferon gamma (IFN-) and tumor necrosis factor-alpha (TNF-), two cytokines associated to the SASP, act as natural adjuvant by promoting an immunoreaction