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Nat Rev Microbiol 6:199210

10.1017/S0007114511000274 33 LiuX.WangY.HoeflingerJ

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Compared with other forms of cell death such as apoptosis, necrosis, and autophagy, ferroptosis exhibits distinct molecular mechanisms and biological features ( Table 1 ): (1) Iron Dependence: Ferroptosis is uniquely triggered by elevated intracellular iron levels, differentiating it from other cell death modes