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N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent ophthalmic drug in treatment of human cataracts

Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was performed using the StepOne Real-Time PCR System (Thermo Fisher Scientific, Waltham, MA) and THUNDERBIRD SYBR qPCR Mix (Toyobo)

Higher levels of protein oxidation markers and reduced activity of important redox enzymes responsible for GSH metabolism have been reported [3] but are not present in all brain regions [8,9]