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[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Fasano A

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Stem cell, Granulocyte-Colony Stimulating Factor and/or Dihexa to promote limb function recovery in a rat sciatic nerve damage-repair model: Experimental animal studies

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This activation: Promotes directed cell migration toward injury sites Enhances cellular outgrowth from damaged tissue edges Improves cell survival during the stressful healing process Facilitates proper tissue organization This mechanism is particularly relevant for tendon and ligament healing, where cellular organization and proper fiber alignment are critical for functional recovery