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Improvements were seen in patient ratings of tinnitus severity, annoyance, unpleasantness, and discomfort

Multiple comparisons were controlled for by Benjamini-Hochberg correction

Study Design Type: Phase 3a, 68-week, multicenter, double-blind, placebo- and active-controlled trial Population: 3417 adults

Cagrilintide Storage & Handling Cagrilintide Storage Reference State Lyophilized (powder) Storage -4F (-20C) freezer Duration Up to 24 months State Lyophilized (short-term) Storage 35.6-46.4F (2-8C) refrigerator Duration Acceptable for shipping or short storage State Reconstituted (liquid) Storage 35.6-46.4F (2-8C) refrigerator Duration 28-30 days

AOD-9604, a modified fragment of human growth hormone, enhances fat metabolism in animal models