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In addition, Orai1, a Ca 2+ channel, has emerged as a key regulator of reactive astrocytes by controlling the synthesis and release of a broad range of proinflammatory mediators 113

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Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: results of a pilot clinical trial

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