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As Mark Hyman, M.D., writes in a post on his blog titled Essential Glutathione: The Mother of All Antioxidants, poor diet, pollution, toxins, medications, stress, trauma, aging, infections and radiation all deplete the bodys GSH stores (3)

doi: 10.1016/j.toxlet.2014.11.027

Jain and Parsanathan, 2020)

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During the process, Glu signaling usually interacts with other signaling molecules such as chemical signaling (Ca 2+ , ROS, NO) and electrical signaling, which in turn takes shape a sophisticated signaling network, eventually regulating accurately plant growth, development, and defense response ( Figure 2 )