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12 mg remains the highest-efficacy dose, but it carries a meaningfully worse GI burden and a correspondingly higher dropout risk

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The peptide powerfully modulates inflammation by increasing microRNA-146a expression while decreasing pro-inflammatory cytokines including TNF-alpha, IL-6, IRAK1, and TRAF6

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Current scientific evidence includes extensive animal studies, which demonstrate enhanced tendon, ligament, and muscle repair, improved angiogenesis, and anti-inflammatory effects, providing mechanistic insight into its regenerative potential