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Zhu L, Xu L-Z, Zhao S, Shen Z-F, Shen H, Zhan L-B

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FEBS Letters, 582(17), 26552662

Endothelial cells line the inner layer of blood vessels that keep micro- and macro-vascular health by sensing pathogen/danger signals and secreting vasoactive (e.g., vasorelaxing and vasoconstricting) molecules and are essential for maintaining tissue homeostasis ( The prothrombotic phenotype and diffuse intravascular coagulation observed in COVID-19 also reflect ED ( Endothelial cell integrity is significantly affected by the cytokine storm induced by COVID-19