BPC157 rescued NSAID-cytotoxicity via stabilizing intestinal permeability and enhancing cytoprotection
Finally, to evaluate industrial applicability of the selected high-glutathione-producing strain, fermentation was conducted using cost-effective agro-industrial byproductsmolasses and corn steep liquor (CSL)as carbon and nitrogen sources (Hajar-Azhari et al., 2018
C (101 MHz, MeOD): 174.50 (C), 172.86 (C), 172.59 (C), 171.54 (C), 171.49 (C), 161.44 (q, J = 37.1 Hz, CF 3 C O), 136.29 (d, J = 3.1 Hz, CH), 134.82 (d, J = 9.9 Hz, CH), 131.54 (d, J = 12.5 Hz, CH), 119.94 (d, J = 86.3, C), 53.79 (CH), 53.55 (CH), 43.42 (CH 2 ), 41.83 (CH 2 ), 40.75 (CH 2 ), 40.23 (CH 2 ), 32.39 (CH 2 ), 29.47 (CH 2 ), 28.74 (d, J = 16.9 Hz, CH 2 ), 27.05 (CH 2 ), 23.15 (d, J = 4.4 Hz, CH 2 ), 22.67 (d, J = 51.3 Hz, CH 2 )
The glutaredoxin (Grx) system, another key player, operates in close association with the GSH pool and serves primarily to regulate protein thiol redox status through reversible de-glutathionylation
However, high doses may not provide extra benefits and should be avoided
