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511,512 Recent research has shown that the activity of p38 is influenced not only by the interplay of upstream regulatory kinases and phosphatases but also by the incorporation of redox modifications on p38

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doi: 10.1530/RAF-23-0024 83 SkinnerMKManikkamMGuerrero-BosagnaC

Currently used diagnostic biomarker methods, such as cerebrospinal fluid (CSF) analysis and positron emission tomography (PET) imaging, provide valuable information but are invasive, expensive and not suitable as a front-line screener 5,7