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The only significant decrease of determined parameters was found for GSH levels

Glutathione supplementation during tirzepatide treatment targets oxidative stress generated by rapid fat mobilization, potentially reducing fatigue and supporting hepatic detoxification pathways activated during weight loss

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Safety monitoring: More frequent blood pressure checks (peptides may affect pressure in vulnerable elderly), kidney function monitoring if long-term use, medication interaction review with physician or pharmacist, close observation for confusion or side effects