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The linkers used for constructing ncAA incorporated bispecific nanobodies were heterobifunctional chemical crosslinkers BCN (Bicyclononyne, MW 401.2287) and Tet (Tetrazine, MW 387.1), which were obtained from commercial sources and used without further purification

21 However, statistical significance was inconsistent in the two outcomes of diabetic neuropathy 5,218 and Alzheimers disease