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BPC-157 (Body Protection Compound-157) is a 15-amino-acid peptide fragment derived from human gastric juice, studied for its cytoprotective and tissue-repair properties across gastrointestinal, musculoskeletal, and neurological systems [1] [2]

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These processes not only compromise cellular bioenergetics but also trigger immune responses through sensors such as cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes (STING), or activate NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasomes, leading to secretion of proinflammatory cytokines such as interleukin (IL)-1 (Mills et al., 2017)

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