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a 14-day continuous course was well-tolerated and effective in human trials [2]

BozkurtNCKarbekBUcanBSahinMCakalEOzbekMet al

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Renjith, I find the 15-PGDH inhibition approach particularly compelling because it targets endogenous chondrocytes rather than relying on stem-cell therapy, positioning it as a potential first-in-class disease-modifying therapy for osteoarthritis

Once the solicitation opens on January 8, direct communication with the topic authors will no longer be allowed, so use this period wisely to refine your approach