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Hypertriglyceridemia-induced acute pancreatitis: progress on disease mechanisms and treatment modalities

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Supporting this, promoter analysis of the human CYP51A1 gene in JEG-3 cellsengineered to overexpress sterol regulatory element-binding protein 1a (SREBF1a)confirmed the presence of multiple regulatory motifs, including a GC box, a cAMP response element (CRE), and a sterol regulatory element (SRE), indicating that human CYP51A1 transcription is co-regulated by both cAMP- and sterol-dependent pathways [37]

Previous studies have shown that OPZ requires metabolite bioactivation both to display potent schistosomicidal activity and inhibition of the GSSG reduction activity [58]

Principles of long-term dynamics of dendritic spines. J Neurosci 28(50): 13592-608