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While pharmacological treatments and phytochemicals could provide symptomatic relief and neuroprotective effects, their efficacy is hindered by poor bioavailability, systemic side effects, and restricted BBB penetration

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It regulates cytokines (TNF-, IL-6), decreases swelling, and limits immune-cell overactivity

3.2 Age and gender Conventional opinion is that Hcy level increases with age ( 3.3 Dietary and nutritional factors Long-term consumption of protein leads to excessive intake of methionine which in turn raises Hcy level, while eating large amounts of vegetables and fruits can indirectly reduce Hcy level by increasing vitamin content