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Klement RJ, Frobel T, Albers T, Fikenzer S, Prinzhausen J

The inotropic effect is augmented by caffeines inhibition of phosphodiesterase, which increases the concentration of cAMP in the myocardium and enhances the intracellular influx of calcium ions into cardiomyocytes

Because of its role in wound healing and hair follicle health, it's also used in treatments to help speed up recovery from minor injuries and to support a healthier, fuller head of hair.

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PK/PD profiling: Investigating absorption, distribution, half-life, and exposureresponse relationships, including the impact of lipidation on duration of action