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306 , F75F84 (2014)

Extracellular NM released by dying dopaminergic neurons plays a critical role in triggering chronic neuroinflammation in PD

But heres what researchers discovered: when you concentrate this peptide and deliver it systemically, it can promote healing throughout your entire body

As shown in an earlier publication, unconjugated bilirubin stimulates microglia primary cultures to respond by acquiring a phagocytic phenotype, which is transformed into an inflammatory response featuring secretion of the pro-inflammatory cytokines interleukin (IL)-1, IL-6, and tumor necrosis factor (TNF)-, increased regulation of cyclooxygenase (COX)-2, and enhanced the activities of MMP- 9 and -2 (188)