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Collectively, the Akt/mTOR/HIF-1 axis coordinates metabolic and epigenetic reprogramming to drive and maintain trained immunity, representing a potential target for therapeutic intervention

Such collaboration will accelerate the transformation of groundbreaking laboratory discoveries into tangible therapies that benefit patients

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Kasthuri N, Hayworth KJ, Berger DR, Schalek RL, Conchello JA, Knowles-Barley S, et al