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At its core dementia results from a combination of diminished synaptic connectivity among neurons and neuronal death in the entorhinal cortex, hippocampus and neocortex

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Moreover, the phytocompound has even been reported to improve cognitive and motor deficits in mouse studies of the same diseases (Schepici et al., 2020) (Table 2)

8 Translational and clinical implications The convergent yet distinct neurobiological actions of Rhodiola rosea , Ginkgo biloba , and Withania somnifera (Ashwagandha) provide a mechanistically informed framework for their rational translation into clinical practice