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(Peptide Sciences) The result: a novel senolytic (literally senescent cell-killing) peptide, offering a more targeted alternative to older senolytics that rely on broad stress induction or BCL2-inhibition

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Amgen's MariTide Phase 2 showed no weight loss plateau at 52 weeks (Nov 2024): The absence of a weight loss plateau effect which both semaglutide and tirzepatide display would be a clinically meaningful differentiation if confirmed in Phase 3, potentially enabling greater sustained weight loss

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RESULTS Analysis of our previously published RNAseq dataset E-MTAB-3808 revealed up-regulation of genes involved in the KEGG (Kyoto Encyclopedia of Genes and Genomes) Pathway Glutathione Metabolism in CSC-enriched cultures compared to their differentiated counterparts