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Additionally, Oga heterozygous ( Oga +/ ) mice, which exhibit chronically elevated levels of O-GlcNAcylation, display antidepressant-like behaviors, and altered synaptic transmission in the medial prefrontal cortex (mPFC) [46]

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TUNEL method revealed a marked accumulation of DNA fragments in both the cytoplasm and nucleus of necrotic hepatocytes in the Aldh2*2 KI homozygous mice after AA exposure (Fig