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As 3 mM of H 2 O 2 has a fusion-promoting effect equivalent to 0.5 M ML162 in C
albicans and influence fungal virulence (Lu et al., 2 production was decreased while prostacyclin and thromboxane production were increased in hypoxia (Blumenstein et al., 2 production in macrophages was significantly reduced and that in urine, the level of PGE 2 in the NOS deficient groups was decreased by 78% compared to the control groups (Marnett et al., 2 induced by LPS (Devaux et al., 2 via COX-2-independent mechanisms
Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations 8-OH-dg: 8-hydroxy-2-deoxyguanosine AM: airway macrophage BAL: bronchoalveolar lavage ELF: epithelial lining fluid GSH: glutathione (reduced form) GSSG: glutathione disulfide (oxidized form) HAT: histone acetyltransferase HDAC: histone deacetylase ICS: inhaled corticosteroid MDA: malondialdehyde PARP: poly (ADP-ribose) polymerase References Fitzpatrick AM, Gaston BM, Erzurum SC, Teague WG 2006 Features of severe asthma in school-age children: atopy and increased exhaled nitric oxide
Nanoparticle-mediated brain-specific drug delivery, imaging, and diagnosis
