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In murine models of allergic airway inflammation, melatonin reduced eosinophilia, type 2 cytokine production, and airway hyperreactivity without altering ILC2 abundance

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Its effects on tendon healing appear mediated through increased expression of growth hormone receptor and upregulation of tendon-specific markers

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For example, sirtuins use NAD+ to help regulate cell health and PARPs use it to help repair damaged DNA