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Abnormal iron metabolism is a significant trigger for ferroptosis, with iron-related proteins including transferrin receptor protein 1 (TfR1), ferritin (FTH and FTL), and iron export proteins playing essential roles in iron homeostasis

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After the TMB substrate solution is added, only those wells that contain GSTo1, biotin-conjugated antibody, and enzyme-conjugated Avidin will exhibit a change in color

Currently developed DPP1 inhibitors are all oral formulations, while many NSP inhibitors require inhalation administration ( However, DPP1 inhibition also has some potential disadvantages, including slower onset (approximately 20 days to achieve maximum effects) and possible systemic side effects such as hyperkeratosis and periodontitis