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In rodent models, the cortical application of potassium chloride has been found to induce CSD and CGRP release [34]

13,168 Diagnosis involves a comprehensive clinical evaluation, including detailed neurological examination, electrophysiological studies like NCS and electromyography (EMG) to assess motor and sensory fiber function and localize lesions, as well as imaging studies such as magnetic resonance imaging (MRI) to exclude compressive or structural causes