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Threats to honey bee health include pathogens, agrochemicals, pollutants, dwindling food sources, and climate change 9,10,11,12

The complete PE-22-28 guide explores these mechanisms in greater detail

Olaparib is a compound that effectively inhibits PARP1 and PARP2, binding to the catalytic domain and preventing the transfer of ADP-ribose units from NAD + to target proteins, thus lowering NAD + consumption 160,161

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The buffering capacity is relatively high in the cytosol and blood, whereas this capacity is low in interstitial fluid where the presence of buffering factors, such as proteins, is limited [17,18]