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Therefore, nanobodies are no longer seen as an alternative to conventional monoclonal antibodies and are rationally designed to deal with complex application scenarios and change the pattern of disease treatment 11

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The clusters of 0 to 10% D 2 O abundance were clustered in one group whereas the clusters of 20%, 40%, 50% and 100% clustered with minimal overlapping

Thermogravimetric analysis (TGA) was carried out on a Perkin-Elmer TGA instrument, from room temperature to 900 C at a heating rate of 10 C min 1 under N 2 atmosphere

The reference standard is scintigraphy : a test meal is labeled with a radioisotope, and a gamma camera tracks how quickly the labeled contents leave the stomach, yielding a half-emptying time (the T values quoted earlier for pramlintide came from this class of method)