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Taking all this into account, pericytes may thus represent and early and interesting therapeutic target, at the BBB level, to fight AD progression

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Therefore, identifying drugs or targets activating Shh signaling pathway may exert neuroprotective effects by inhibiting microglial activation and reducing inflammation following OGD/R injury or cerebral ischemic injury

An association between ROS levels and IFN- response in HIV-1 infection has been reported, whereby HIV-1 reverse transcriptase enzyme-induced increased ROS levels induce stronger IFN- responses 115