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Front Pharmacol (2015) 6:262

In some embodiments, the otoprotectant is a compound of Formula (VIII) having the structure of Formula (VIIIa): In some embodiments, the otoprotectant is a compound of Formula (IX): wherein: R 1 is C 6 -C 10 aryl or C 3 -C 9 heteroaryl, wherein C 6 -C 10 aryl and C 3 -C 9 heteroaryl are optionally substituted with one or more R 4

Thornalley and Vask 1985)

Administration : Subcutaneous or intramuscular injection, sometimes near the injury site

SkinCeuticals launched its first vitamin C serum in 1997, so it can take a lot of credit for the explosion of the entire antioxidant skin-care category