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A serious systemic disturbance called metabolic acidosis can occur in CKD when acidic compounds, especially nitrogen-containing waste from dietary protein metabolism, accumulate in the blood

Autonomic nerves, which control both voluntary and involuntary bodily functions such as blood pressure, may also be affected

*Correspondence: Ming Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Redondo P, Guzmn M, Marquina M, Pretel M, Aguado L, Lloret P