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Development of inhaled DPP1 inhibitors aims to optimize treatment safety and efficacy by directly acting on lung target organs ( Precision medicine for DPP1 inhibitor therapy hinges on identifying the right patientsparticularly those with high sputum neutrophil counts and NSP activity, who tend to respond better to treatment ( Development of novel DPP1 inhibitors continues advancing

S.ChaeY.et al (2010)

But peptides remain difficult to deliver across oral mucosa

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In MI, complete coronary artery occlusion is accompanied by a variety of structurally and functionally adverse consequences, the most irreversible of which is myocardial cell death