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This risk shifted attention toward metformin, whose milder pharmacologic profile offered a better safety margin and lower propensity for lactic acidosis

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The test is intended to be used in conjunction with other available clinical information as an aid to identify patients eligible for treatment with Sarepta Therapeutics, Inc.'s (NASDAQ: SRPT) ELEVIDYS (delandistrogene moxeparvovec-rokl), gene therapy for certain individuals with Duchenne muscular dystrophy