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These approaches aim to enhance treatment efficacy while reducing damage to the normal hematopoietic system, either by selectively inducing LSC clearance or remodeling the bone marrow immune microenvironment

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doi: 10.1021/ja411006a 248 LinkermannASkoutaRHimmerkusNMulaySRDewitzCDe ZenFet al

Phenylephrine has been determined to be no more effective than placebo when taken orally (Drug Safety and Availability, 2023)