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A 2025 matched-cohort study found men who started testosterone therapy had significantly higher rates of tendon tears and repairs at one and two years compared to controls, a pattern the authors attributed to testosterone's effect on tendon biomechanics outpacing the tissue's regenerative capacity Sherman et al

These pathways can interact and increase overall immune reactivity

Helm, J., Schls, L

Ethical statement and Biobank agreements Ethics committee of the hospital district of Uusimaa and Helsinki gave ethical approval for collection of the in-house control blood samples

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