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Sulfonylureas have no significant effects on circulating triglycerides, lipoproteins or cholesterol

Importantly, most of the above mentioned IF-mediated alterations in the eWAT immune compartment were absent in the HFD-IF-KO group, underscoring a major role for p53 in AT inflammation upon IF

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However, some controversial data exist, with some authors reporting less favourable results with P-15-containing graft substitutes [125, 126]

The cDNA for SLC7A11 coding region was amplified from ZR-75-1 breast cancer cell line using standard RT-PCR and ligated into EcoR I- Sal I linearized retroviral pBabe-hygro vector, generating the pBabe-hygro-SLC7A11