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Schizophrenia For decades ago, there was a report of MTHFR enzymatic activity reduction in two schizophrenia patients which were 18 and 21% percent of the normal level, respectively, while homocysteine remethylation was also defected 42

In aerobic organisms, the sulfane sulfur of LMW persulfides is oxidized to sulfite, regenerating the LMW thiol species 22

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196 Its expression is upregulated by LPS and TNF, and the mechanism involves direct regulation by the transcription factor NF-B