Despite some similarities such as promoting reduced body weight [13], substantial differences between CR and IF have been uncovered [5] and are, indeed, expected, since CR involves a daily reduction in food intake, while IF changes feeding frequency, and may not always result in a limitation of food ingestion [7, 14]
Dysbiosis during this transition underlies elevated ketosis risk: the decline of VFA-producing taxaincluding Ruminococcus , Prevotella , Selenomonas , and Succinivibrionaceaeimpairs propionate fermentation pathways and reduces gluconeogenic precursor supply, while the concurrent expansion of opportunistic taxa such as Mycoplasma and Saccharimonas further destabilizes ruminal homeostasis (Table 2), collectively contributing to hypoglycemia, excessive mobilization of body fat, and ketone accumulation, which compromise lactation, reproductive performance, and offspring health 47,55,56,57
Phosphoglycerate mutase family member 5 maintains oocyte quality via mitochondrial dynamic rearrangement during aging
doi: 10.1371/journal.pone.0123454 Stupnisek M, Franjic S, Drmic D, et al
Various studies have explored gingers biological activity, the active components that contribute, and their mechanism of action (12)
