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doi: 10.2217/nmt-2020-0033 241 SamaR

It signals fibroblasts to produce collagen and elastin, accelerates wound and tissue remodeling, and shifts gene expression toward repair

Because neither compound is licensed in the UK, no formal pharmacokinetic or pharmacodynamic interaction studies have been conducted or reviewed by the MHRA

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Figure 33 shows the time course of drug accumulation during a constant-rate drug infusion and the time course of drug elimination after stopping an infusion that has reached steady state