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This article covers meal-timing strategies, how circadian rhythm affects tolerability, what preparation mistakes negate efficacy entirely, and how to adjust timing if you experience persistent nausea or hypoglycemia

May 1 2020;98(5)doi:10.1093/jas/skaa128

Individuals With Malabsorption Conditions Certain medical conditions and medications can interfere with B12 absorption, including: Pernicious anemia (an autoimmune condition that impairs intrinsic factor production necessary for B12 absorption)[12]

Historically, mean weight loss has been modest with AOMs although with newer agents and combination therapy, higher degrees of weight loss can be achieved

Patients should always follow provider instructions carefully