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The key to the controversy surrounding the administration of NAC in these cases may be that these patients have depleted ATP and the last reaction of the detailed cycle (glutathione synthetase) is limited and GSH is not synthesized

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In the skin, photoprotection by carotenoids occurs by direct absorption of UVA, UVB, and VL by acting against the action of UVR on exposed molecules, which become unstable and potentially hazardous to the DNA molecules and cellular proteins

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This effect is particularly relevant in the early stages of hard callus formation when osteoblast recruitment and activity are critical