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Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of alpha-synuclein preformed fibrils

10.1093/jbcr/iraa127 J Burn Care Res

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Although protein aggregation is a common feature, neurodegenerative diseases exhibit different patterns of neurons loss and affect distinct regions of the CNS (Dugger and Dickson, 2017)