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83 , 84 , 85 For example, based on data from a study in Europe and a study in the United States, of people age 6569, the risk of developing dementia by the early to mid80s was 5% to 7% among those with no copies of the e4 form, 15% to 16% among those with one copy, and 31% to 40% among those with two copies

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Spermidine did not alter lipid levels, blood chemistry or haematological parameters (Reference Keohane, Everett and Pereira105)