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This analysis provides a useful overview of 18 studies, and also demonstrates that male sex and younger age may be associated with a stronger protective effect of UA

650 Methyl ferulic acid inhibits the expression of NOX4 protein and alleviates neuropathic pain in mice by regulating the expression of ACSL4 and GPX4, as well as ROS and iron content, suggesting that inhibiting NOX4-induced ferroptosis can reduce neuropathic pain

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Biochim Biophys Acta 1790 : 878885

doi: 10.3389/fendo.2023.1154561 Received 30 January 2023 Accepted 07 April 2023 Published 19 May 2023 Volume 14 - 2023 Edited by Mikiko Watanabe, Sapienza University of Rome, Italy Reviewed by Jessica Ferrell, Northeast Ohio Medical University, United States Updates Copyright 2023 Garruti, Baj, Cignarelli, Perrini and Giorgino