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Among these, the MUC5B promoter variant (rs35705950) is the most prominent, conferring a greater than threefold increased risk for IPF and exceeding the effect of all other known variants combined [21, 22]

With further in-depth analysis of its regulatory network and continued optimization of activator design, SIRT1 holds significant potential as a breakthrough target for multi-pathway, systemic, and precise intervention in MASLD

In vivo studies Effect of BER chitosomes and BER solution on motor activity, coordination, and balance in rat model of parkinsonism The degeneration of dopaminergic neurons is responsible for motor dysfunction in PD patients [92]